In the fifth round of the 2025/26 UEFA Champions League, Manchester City, playing at the Etihad Stadium, suffered a 0-2 defeat to Bundesliga side Bayer Leverkusen after conceding goals in both halves.

Six minutes into the game, Manchester City's corner kick was cleared, and Savio got the ball and took a shot, but it was blocked. Then Ake received a pass back from Oscar Bob and took another shot, but the ball was blocked by Bayer Leverkusen goalkeeper Mark Flecken.

In the 12th minute, Bayer Leverkusen created an attacking opportunity on the left flank, with Ernest Poku taking a shot, but it was blocked by Manchester City defender Ete Nouri. In the 17th minute, Ernest Poku was brought down by Ete Nouri while dribbling forward, but the referee did not award a penalty.

In the 23rd minute, Cofane passed the ball back from the penalty area to Grimaldo, who immediately volleyed it into the net, giving Leverkusen a 1-0 lead. In the 44th minute, Oscar Bob received the ball and entered the penalty area before crossing it, but Leverkusen goalkeeper Mark Flecken immediately rushed out to deny Manchester City's shot.

In the 45th minute, Manchester City continued their counter-attack. Reindes gained possession and dribbled into the penalty area before unleashing a powerful shot, but it was blocked by Bayer Leverkusen goalkeeper Mark Flecken.

At the start of the second half, Manchester City substituted Doku, Foden, and Nico Aureli for Oscar Bob, Rico Lewis, and Ete Nouri. In the 53rd minute, Nico Aureli received a cross from his teammate outside the penalty area and took a long-range shot, but the angle was too straight and the ball was easily caught by Bayer Leverkusen goalkeeper Mark Flecken.

In the 54th minute, Ibrahim Maza chipped a pass from the attacking third into the penalty area, where Patrick Schick headed the ball past Aké to extend Bayer Leverkusen's lead to 2-0. In the 65th minute, Reindes took a corner kick, and Malmush's shot went wide.

Subsequently, Manchester City substituted Haaland and Rajan Serki for Malmush and Husanov. In the 67th minute, Manchester City attempted a counter-attack, with Haaland's header going wide. In the 70th minute, Haaland received a pass from Foden and entered the penalty area, but his shot was saved by Bayer Leverkusen goalkeeper Mark Flecken.

In the 76th minute, Haaland controlled the ball in the penalty area and volleyed, but the ball went over the post. In the 86th minute, Manchester City won a free kick. Rajen Scherki took the free kick and shot directly, but Bayer Leverkusen goalkeeper Mark Flecken jumped up and blocked the ball.

In the 90th minute, Haaland received the ball and entered the penalty area to shoot, but his shot was cleared by the opposing player. Doku then tried to shoot, but his shot was also blocked.

Manchester City ultimately lost 0-2 to Bayer Leverkusen.